When working with large systems containing multiple bilayers or other dynamic macroscopic objects, it tends to come more natural to give these aggregates an identity of their own. This is exactly what MDAVoxelSegmentation does for amphipathic Martini systems. It not only detects bilayers/leaflets or other aggregates using a voxel based architecture, but it also keeps track of such entities over time. For more information take a look at the github or contact the developers! As an appetizer we added a rendered movie and graph describing how the transfection of dsDNA from a lipid-DNA complex occurs over a membrane (doi: 10.7554/eLife.52012).