DAFT - Docking Assay For Transmembrane Components
- Last Updated: Wednesday, 22 April 2015 11:41
DAFT is a method for investigating protein-protein and protein-lipid interactions by running many association simulations. These allow identifying the binding hotspots and alternative binding sites.
DAFT is a bundle of programs and supporting files, and comprises martinize, martinate, insane, and several MARTINI interaction table generating Python scripts, toghether with the standard lipid, ion and solvent topologies. The user interface is formed by the bash script daft.sh (see daft.sh -h for more information).
More background on this DAFT approach can be read in the DAFT paper: DOI: 10.1021/ct5010092