New on the Martini pages

Recently, we have added a few new features to the Martini-website. First, there is the Martini-flowchart: if you want to start a new project using the Martini force field but have now idea where to start, this flowchart will get you started step-by-step. Second, we recently started writing a group weblog. Different* group-member will post on a regular* basis what comes to mind related* to the work in the lab. *These terms have to be taken with a grain of salt.

Martini perspective

A review of the Martini force field has appeared, with an overview of one decade of Martini applications, discussion of its limitations, and an outlook on future developments:
S.J. Marrink & D.P. Tieleman, "Perspective on the Martini model",  Chem. Soc. Rev., 42:6801-6822, 2013. Open access

Glycolipids dominate the world

Martini glycolipid force field releasedglycoworld

C.A. Lopez, Z. Sovova, F.J. van Eerden, A.H. de Vries, S.J. Marrink.
Martini force field parameters for glycolipids.
J. Chem. Theory Comput., 9:1694–1708, 2013. DOI:10.1021/ct3009655

Read more: Glycolipids dominate the world

Martini 2.2


Try out now! Martini 2.2: Improved parameters for the protein force field

D.H. de Jong, G. Singh, W.F.D. Bennett, C. Arnarez, T.A. Wassenaar, L.V. Schäfer, X. Periole, D.P. Tieleman, S.J. Marrink
Improved Parameters For The Martini Coarse-Grained Protein Force Field, J. Chem. Th. Comp, 9:687–697, 2013. DOI:10.1021/ct300646g


Curious? Go here for downloading the Martinize script which now features a beta release of Martini 2.2. Any feedback is appreciated so we can further improve the model.

Read more: Martini 2.2

Dimerization of GPCRs


First report on the free energy surface of membrane protein dimerization

X. Periole, A.M. Knepp, T.P. Sakmar, S.J. Marrink, T. Huber.
Structural determinants of the supra-molecular organization of
G protein-coupled receptors in bilayers.
JACS, 134 (26), pp 10959–10965. abstract

Read more: Dimerization of GPCRs