Penetrating PEGylated lipid nanodiscs
- Last Updated: Wednesday, 08 June 2022 08:59
Impressive work on using lipid nanoparticles to deliver drugs to tumour cells, featuring large scale Martini simulations. Snapshots show the difference in penetration efficiency between a PEGylated lipid nanodisc (a) and a PEGylated liposome (b), both with a diameter of 40 nm, before (t = 0 ns) and after (t = 1,750 ns) being pulled through a 20 nm pore. For details, see Dane et al., Nature Materials, 2022.